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Oct 022012

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However, the current study is the most extensive to date in terms of the number of genes and the coverage of different neural tissues. A correlation matrix of brain region relatedness was generated for all pairwise comparisons.


Any copying, republication or redistribution of Lipper content, including by caching, framing or similar means, is expressly prohibited without the prior written consent of Lipper. The algorithms and criteria used to analyze the gene expression data in TeraGenomics are described in Supporting Methods, which is published as supporting information on the PNAS web site.



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Reader Comments

  1. The following body regions were collected: A reference document was created that consisted of photographs and atlas bregma coordinates to illustrate the exact methods used to dissect each region, including step-by-step instructions for an example, see Appendix 1, which is published as supporting information on the PNAS web site.

  2. Our current understanding of brain architecture and organization is based on studies of embryology, anatomy, and evolution in which direct observation of anatomic structures was the foundation for postulated models of brain structure 1.

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